Publication Beamlines
Abbas, Yazan M.; Laudenbach, Beatrice Theres; Martínez-Montero, Saúl; Cencic, Regina; Habjan, Matthias; Pichlmair, Andreas; Damha, Masad J.; Pelletier, Jerry; Nagar, Bhushan (2017). Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations. Proceedings of the National Academy of Sciences 114(11) , E2106-E2115. 10.1073/pnas.1612444114. [PDB: 5udi, 5udk, 5udl] CMCF-ID
Boniecki, Michal T.; Freibert, Sven A.; Mühlenhoff, Ulrich; Lill, Roland; Cygler, Miroslaw (2017). Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex. Nature Communications 8(1) . 10.1038/s41467-017-01497-1. [PDB: 5wkp, 5wlw] CMCF-ID
Cook, Jonathan D.; Sultana, Azmiri; Lee, Jeffrey E. (2017). Structure of the infectious salmon anemia virus receptor complex illustrates a unique binding strategy for attachment. Proceedings of the National Academy of Sciences , 201617993. 10.1073/pnas.1617993114. [PDB: 5t96, 5t9y] CMCF-ID
Copp, William; Denisov, Alexey Y.; Xie, Jingwei; Noronha, Anne M.; Liczner, Christopher; Safaee, Nozhat; Wilds, Christopher J.; Gehring, Kalle (2017). Influence of nucleotide modifications at the C2 prime position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA. Nucleic Acids Research . 10.1093/nar/gkx713. [PDB: 5vxq] CMCF-ID
Crawford, Terry D.; Audia, James E.; Bellon, Steve; Burdick, Daniel J.; Bommi-Reddy, Archana; Côté, Alexandre; Cummings, Richard T.; Duplessis, Martin; Flynn, E. Megan; Hewitt, Michael; Huang, Hon-Ren; Jayaram, Hariharan; Jiang, Ying; Joshi, Shivangi; Kiefer, James R.; Murray, Jeremy; Nasveschuk, Christopher G.; Neiss, Arianne; Pardo, Eneida; Romero, F. Anthony; Sandy, Peter; Sims, Robert J.; Tang, Yong; Taylor, Alexander M.; Tsui, Vickie; Wang, Jian; Wang, Shumei; Wang, Yongyun; Xu, Zhaowu; Zawadzke, Laura; Zhu, Xiaoqin; Albrecht, Brian K.; Magnuson, Steven R.; Cochran, Andrea G. (2017). GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2). ACS Medicinal Chemistry Letters 8(7) , 737-741. 10.1021/acsmedchemlett.7b00132. [PDB: 5v84] CMCF-ID
Curtin, Michael L.; Pliushchev, Marina A.; Li, Huan-Qiu; Torrent, Maricel; Dietrich, Justin D.; Jakob, Clarissa G.; Zhu, Haizhong; Zhao, Hongyu; Wang, Ying; Ji, Zhiqin; Clark, Richard F.; Sarris, Kathy A.; Selvaraju, Sujatha; Shaw, Bailin; Algire, Mikkel A.; He, Yupeng; Richardson, Paul L.; Sweis, Ramzi F.; Sun, Chaohong; Chiang, Gary G.; Michaelides, Michael R. (2017). SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding. Bioorganic & Medicinal Chemistry Letters 27(7) , 1576-1583. 10.1016/j.bmcl.2017.02.030. [PDB: 5u69, 5u6d] CMCF-ID
Eastman, Kyle J.; Parcella, Kyle; Yeung, Kap-Sun; Grant-Young, Katharine A.; Zhu, Juliang; Wang, Tao; Zhang, Zhongxing; Yin, Zhiwei; Beno, Brett R.; Sheriff, Steven; Kish, Kevin; Tredup, Jeffrey; Jardel, Adam G.; Halan, Vivek; Ghosh, Kaushik; Parker, Dawn; Mosure, Kathy; Fang, Hua; Wang, Ying-Kai; Lemm, Julie; Zhuo, Xiaoliang; Hanumegowda, Umesh; Rigat, Karen; Donoso, Maria; Tuttle, Maria; Zvyaga, Tatyana; Haarhoff, Zuzana; Meanwell, Nicholas A.; Soars, Matthew G.; Roberts, Susan B.; Kadow, John F. (2017). The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase. MedChemComm . 10.1039/c6md00636a. [PDB: 5twn] CMCF-ID
Eble, Johannes A.; McDougall, Matthew; Orriss, George L.; Niland, Stephan; Johanningmeier, Benjamin; Pohlentz, Gottfried; Meier, Markus; Karrasch, Simone; Estevão-Costa, Maria Inacia; Martins Lima, Augusto; Stetefeld, Jörg (2017). Dramatic and concerted conformational changes enable rhodocetin to block α2β1 integrin selectively. PLoS Biology 15(7) , e2001492. 10.1371/journal.pbio.2001492. [PDB: 5thp] CMCF-ID
El-Halfawy, Omar M.; Klett, Javier; Ingram, Rebecca J.; Loutet, Slade A.; Murphy, Michael E. P.; Martín-Santamaría, Sonsoles; Valvano, Miguel A. (2017). Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance. mBio 8(2) , e00225-17. 10.1128/mbio.00225-17. [PDB: 5ixg, 5ixh] CMCF-ID
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Mazhab-Jafari, Mohammad T.; Benlekbir, Samir; Guarné, Alba; Rubinstein, John L.; Julien, Jean-Philippe (2017). Molecular basis of human CD22 function and therapeutic targeting. Nature Communications 8(1) . 10.1038/s41467-017-00836-6. [PDB: 5vkj, 5vkk, 5vkm, 5vl3] CMCF-ID
Fong, Desiree H.; Burk, David L.; Blanchet, Jonathan; Yan, Amy Y.; Berghuis, Albert M. (2017). Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure . 10.1016/j.str.2017.03.007. [PDB: 5igi, 5igh, 5igj, 5igp, 5igr, 5igs, 5igt, 5igu, 5igv, 5igy, 5igz, 5ih0, 5ih1, 5iwu] CMCF-ID
Gorelik, Alexei; Liu, Fangyu; Illes, Katalin; Nagar, Bhushan (2017). Crystal Structure of the Human Alkaline Sphingomyelinase Provides Insights into Substrate Recognition. Journal of Biological Chemistry , jbc.M116.769273. 10.1074/jbc.m116.769273. [PDB: 5tcd, 5udy] CMCF-ID
Gorelik, Alexei; Randriamihaja, Antsa; Illes, Katalin; Nagar, Bhushan (2017). A Key Tyrosine Substitution Restricts Nucleotide Hydrolysis by the Ectoenzyme NPP5. FEBS Journal . 10.1111/febs.14266. [PDB: 5vem, 5ven] CMCF-ID
Grochulski, Pawel; Fodje, Michel; Labiuk, Shaun; Wysokinski, Tomasz W.; Belev, George; Korbas, Malgorzata; Rosendahl, Scott M. (2017). Review of Canadian Light Source facilities for biological applications. Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms . 10.1016/j.nimb.2017.01.065. MID-IR, CMCF-BM, CMCF-ID, BMIT-BM, BMIT-ID, BIOXAS
Guo, Shuaiqi; Stevens, Corey A.; Vance, Tyler D. R.; Olijve, Luuk L. C.; Graham, Laurie A.; Campbell, Robert L.; Yazdi, Saeed R.; Escobedo, Carlos; Bar-Dolev, Maya; Yashunsky, Victor; Braslavsky, Ido; Langelaan, David N.; Smith, Steven P.; Allingham, John S.; Voets, Ilja K.; Davies, Peter L. (2017). Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice. Science Advances 3(8) , e1701440. 10.1126/sciadv.1701440. [PDB: 5j6y, 5k8g] CMCF-ID