Publication Beamlines
Abbas, Yazan M.; Laudenbach, Beatrice Theres; Martínez-Montero, Saúl; Cencic, Regina; Habjan, Matthias; Pichlmair, Andreas; Damha, Masad J.; Pelletier, Jerry; Nagar, Bhushan (2017). Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations. Proceedings of the National Academy of Sciences 114(11) , E2106-E2115. 10.1073/pnas.1612444114. [PDB: 5udi, 5udk, 5udl] CMCF-ID
Cook, Jonathan D.; Sultana, Azmiri; Lee, Jeffrey E. (2017). Structure of the infectious salmon anemia virus receptor complex illustrates a unique binding strategy for attachment. Proceedings of the National Academy of Sciences , 201617993. 10.1073/pnas.1617993114. [PDB: 5t96, 5t9y] CMCF-ID
Curtin, Michael L.; Pliushchev, Marina A.; Li, Huan-Qiu; Torrent, Maricel; Dietrich, Justin D.; Jakob, Clarissa G.; Zhu, Haizhong; Zhao, Hongyu; Wang, Ying; Ji, Zhiqin; Clark, Richard F.; Sarris, Kathy A.; Selvaraju, Sujatha; Shaw, Bailin; Algire, Mikkel A.; He, Yupeng; Richardson, Paul L.; Sweis, Ramzi F.; Sun, Chaohong; Chiang, Gary G.; Michaelides, Michael R. (2017). SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding. Bioorganic & Medicinal Chemistry Letters 27(7) , 1576-1583. 10.1016/j.bmcl.2017.02.030. [PDB: 5u69, 5u6d] CMCF-ID
Eastman, Kyle J.; Parcella, Kyle; Yeung, Kap-Sun; Grant-Young, Katharine A.; Zhu, Juliang; Wang, Tao; Zhang, Zhongxing; Yin, Zhiwei; Beno, Brett R.; Sheriff, Steven; Kish, Kevin; Tredup, Jeffrey; Jardel, Adam G.; Halan, Vivek; Ghosh, Kaushik; Parker, Dawn; Mosure, Kathy; Fang, Hua; Wang, Ying-Kai; Lemm, Julie; Zhuo, Xiaoliang; Hanumegowda, Umesh; Rigat, Karen; Donoso, Maria; Tuttle, Maria; Zvyaga, Tatyana; Haarhoff, Zuzana; Meanwell, Nicholas A.; Soars, Matthew G.; Roberts, Susan B.; Kadow, John F. (2017). The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase. MedChemComm . 10.1039/c6md00636a. [PDB: 5twn] CMCF-ID
El-Halfawy, Omar M.; Klett, Javier; Ingram, Rebecca J.; Loutet, Slade A.; Murphy, Michael E. P.; Martín-Santamaría, Sonsoles; Valvano, Miguel A. (2017). Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance. mBio 8(2) , e00225-17. 10.1128/mbio.00225-17. [PDB: 5ixg, 5ixh] CMCF-ID
Fong, Desiree H.; Burk, David L.; Blanchet, Jonathan; Yan, Amy Y.; Berghuis, Albert M. (2017). Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure . 10.1016/j.str.2017.03.007. [PDB: 5igi, 5igh, 5igj, 5igp, 5igr, 5igs, 5igt, 5igu, 5igv, 5igy, 5igz, 5ih0, 5ih1, 5iwu] CMCF-ID
Gorelik, Alexei; Liu, Fangyu; Illes, Katalin; Nagar, Bhushan (2017). Crystal Structure of the Human Alkaline Sphingomyelinase Provides Insights into Substrate Recognition. Journal of Biological Chemistry , jbc.M116.769273. 10.1074/jbc.m116.769273. [PDB: 5tcd, 5udy] CMCF-ID
Grochulski, Pawel; Fodje, Michel; Labiuk, Shaun; Wysokinski, Tomasz W.; Belev, George; Korbas, Malgorzata; Rosendahl, Scott M. (2017). Review of Canadian Light Source facilities for biological applications. Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms . 10.1016/j.nimb.2017.01.065. MID-IR, CMCF-BM, CMCF-ID, BMIT-BM, BMIT-ID, BIOXAS
Hewitt, Stephen Nakazawa; Dranow, David M.; Horst, Benjamin G.; Abendroth, Jan A.; Forte, Barbara; Hallyburton, Irene; Jansen, Chimed; Baragaña, Beatriz; Choi, Ryan; Rivas, Kasey L.; Hulverson, Matthew A.; Dumais, Mitchell; Edwards, Thomas E.; Lorimer, Donald D.; Fairlamb, Alan H.; Gray, David W.; Read, Kevin D.; Lehane, Adele M.; Kirk, Kiaran; Myler, Peter J.; Wernimont, Amy; Walpole, Chris; Stacy, Robin; Barrett, Lynn K.; Gilbert, Ian H.; Van Voorhis, Wesley C. (2017). Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infectious Diseases 3(1) , 34-44. 10.1021/acsinfecdis.6b00078. [PDB: 5ifu] CMCF-ID
Jha, Vikash; Ling, Hong (2017). Structural basis of accurate replication beyond a bulky major benzo[a]pyrene adduct by human DNA polymerase kappa. DNA Repair 49, 43-50. 10.1016/j.dnarep.2016.11.001. [PDB: 5t14] CMCF-ID
Machuqueiro, Miguel; Victor, Bruno; Switala, Jacek; Villanueva, Jacylyn; Rovira, Carme; Fita, Ignacio; Loewen, Peter C. (2017). The Catalase Activity of Catalase-Peroxidases Is Modulated by Changes in the pKa of the Distal Histidine. Biochemistry 56(17) , 2271-2281. 10.1021/acs.biochem.6b01276. [PDB: 5syw, 5kq0, 5kq2, 5kq3, 5kq6, 5kqh, 5kqi, 5kqk, 5ksf, 5ksk, 5txq, 5v4o, 5v53] CMCF-ID
McCallum, Matthew; Tammam, Stephanie; Khan, Ahmad; Burrows, Lori L.; Howell, P. Lynne (2017). The molecular mechanism of the type IVa pilus motors. Nature Communications 8, 15091. 10.1038/ncomms15091. [PDB: 5tsg, 5tsh] CMCF-ID
McPhail, Jacob A.; Ottosen, Erik H.; Jenkins, Meredith L.; Burke, John E. (2017). The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3. Structure 25(1) , 121-131. 10.1016/j.str.2016.11.016. [PDB: 5tdq] CMCF-ID
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L.; Brochu, Denis; Buenbrazo, Nakita; Wakarchuk, Warren; Burke, John E.; Gilbert, Michel; Boraston, Alisdair B. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kdn, 5kdv, 5kdx, 5kd5, 5kd8, 5kdu, 5kdw] CMCF-BM, CMCF-ID
Park, Jaeok; Leung, Chun Yuen; Matralis, Alexios N.; Lacbay, Cyrus M.; Tsakos, Michail; Fernandez De Troconiz, Guillermo; Berghuis, Albert M.; Tsantrizos, Youla S. (2017). Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. Journal of Medicinal Chemistry 60(5) , 2119-2134. 10.1021/acs.jmedchem.6b01888. [PDB: 5juz, 5jv1] CMCF-ID