Publication Beamlines
Grochulski, Pawel; Fodje, Michel; Labiuk, Shaun; Wysokinski, Tomasz W.; Belev, George; Korbas, Malgorzata; Rosendahl, Scott M. (2017). Review of Canadian Light Source facilities for biological applications. Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms . 10.1016/j.nimb.2017.01.065. MID-IR, CMCF-BM, CMCF-ID, BMIT-BM, BMIT-ID, BIOXAS
Hewitt, Stephen Nakazawa; Dranow, David M.; Horst, Benjamin G.; Abendroth, Jan A.; Forte, Barbara; Hallyburton, Irene; Jansen, Chimed; Baragaña, Beatriz; Choi, Ryan; Rivas, Kasey L.; Hulverson, Matthew A.; Dumais, Mitchell; Edwards, Thomas E.; Lorimer, Donald D.; Fairlamb, Alan H.; Gray, David W.; Read, Kevin D.; Lehane, Adele M.; Kirk, Kiaran; Myler, Peter J.; Wernimont, Amy; Walpole, Chris; Stacy, Robin; Barrett, Lynn K.; Gilbert, Ian H.; Van Voorhis, Wesley C. (2017). Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infectious Diseases 3(1) , 34-44. 10.1021/acsinfecdis.6b00078. [PDB: 5ifu] CMCF-ID
Jha, Vikash; Ling, Hong (2017). Structural basis of accurate replication beyond a bulky major benzo[a]pyrene adduct by human DNA polymerase kappa. DNA Repair 49, 43-50. 10.1016/j.dnarep.2016.11.001. [PDB: 5t14] CMCF-ID
McPhail, Jacob A.; Ottosen, Erik H.; Jenkins, Meredith L.; Burke, John E. (2017). The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3. Structure 25(1) , 121-131. 10.1016/j.str.2016.11.016. [PDB: 5tdq] CMCF-ID
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L.; Brochu, Denis; Buenbrazo, Nakita; Wakarchuk, Warren; Burke, John E.; Gilbert, Michel; Boraston, Alisdair B. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kdn, 5kdv, 5kdx, 5kd5, 5kd8, 5kdu, 5kdw] CMCF-BM, CMCF-ID
Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8, 14132. 10.1038/ncomms14132. [PDB: 5ja0] CMCF-ID
Richter, Jeremy M.; Cheney, Daniel L.; Bates, J. Alex; Wei, Anzhi; Luettgen, Joseph M.; Rendina, Alan R.; Harper, Timothy M.; Narayanan, Rangaraj; Wong, Pancras C.; Seiffert, Dietmar; Wexler, Ruth R.; Priestley, E. Scott (2017). Design and Synthesis of Novel Meta-Linked Phenylglycine Macrocyclic FVIIa Inhibitors. ACS Medicinal Chemistry Letters 8(1) , 67-72. 10.1021/acsmedchemlett.6b00375. [PDB: 5tqe] CMCF-ID
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E.; Omichinski, James G. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] CMCF-ID
Almawi, Ahmad W.; Matthews, Lindsay A.; Larasati, ; Myrox, Polina; Boulton, Stephen; Lai, Christine; Moraes, Trevor; Melacini, Giuseppe; Ghirlando, Rodolfo; Duncker, Bernard P.; Guarné, Alba (2016). ‘AND’ logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7. Scientific Reports 6, 34237. 10.1038/srep34237. [PDB: 5t2s] CMCF-BM
Antonacci, P.; Chevalier, S.; Lee, J.; Ge, N.; Hinebaugh, J.; Yip, R.; Tabuchi, Y.; Kotaka, T.; Bazylak, A. (2016). Balancing mass transport resistance and membrane resistance when tailoring microporous layer thickness for polymer electrolyte membrane fuel cells operating at high current densities. Electrochimica Acta 188, 888-897. 10.1016/j.electacta.2015.11.115. BMIT-BM
Argyropoulos, Panos; Bergeret, Fabien; Pardin, Christophe; Reimer, Janice M.; Pinto, Atahualpa; Boddy, Christopher N.; Schmeing, T. Martin (2016). Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. Biochimica et Biophysica Acta (BBA) - General Subjects 1860(3) , 486-497. 10.1016/j.bbagen.2015.11.007. [PDB: 5d3k] CMCF-BM
Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4v, 5f4e, 5f4t] CMCF-ID
Basnayaka, Upekha; Chapman, Dean (2016). Synchrotron Imaging of Ovaries Ex Vivo. Journal of Fertilization In Vitro - IVF-Worldwide Reproductive Medicine Genetics & Stem Cell Biology 04(01) . 10.4172/2375-4508.1000169. BMIT-BM, BMIT-ID
Bawolin, Nahshon; Chen, Xiongbaio (2016). Synchrotron-Based in Situ Characterization of the Scaffold Mass Loss from Erosion Degradation. Journal of Functional Biomaterials 7(3) , 17. 10.3390/jfb7030017. BMIT-BM
Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye; Diaz, Dolores; Dudley, Danette A.; Gaudino, John J.; Gould, Stephen E.; Grina, Jonas; Hunsaker, Thomas; Liu, Lichuan; Martinson, Matthew; Moreno, David; Mueller, Lars; Orr, Christine; Pacheco, Patricia; Qin, Ann; Rasor, Kevin; Ren, Li; Robarge, Kirk; Shahidi-Latham, Sheerin; Stults, Jeffrey; Sullivan, Francis; Wang, Weiru; Yin, Jianping; Zhou, Aihe; Belvin, Marcia; Merchant, Mark; Moffat, John; Schwarz, Jacob B. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] CMCF-ID